Understanding Insulin and Its Impact on the Body

If you are experiencing weight gain, it is time to have your insulin levels measured.
 
Insulin is a peptide hormone made in the pancreas when levels of glucose are detected in the gut that are elevated. Glucose is a simple sugar and a primary source of energy for the body’s cells. Glucose enters the body in forms of monosaccharides (fruit sugar), disaccharides (milk sugar) or polysaccharides (starch). When in excess, the cells store as glycogen which is used in states of fasting or energy necessity. 
 
The hormone insulin coordinates with glucagon to modulate glucose levels. Insulin acts via an anabolic pathway, while glucagon performs catabolic functions. Insulin binds to cell receptors, acting as a gatekeeper, shuttling glucose into cells to be processed into energy, or ATP (adenosine triphosphate). Or it induces glucose storage in the liver, muscles, and adipose tissue, which when in excess will cause weight gain.
 
Insulin can be added to a lab draw which is essential in understanding metabolic status. While the range on a standard lab test is about 2-24 mIU/ml, an optimal range is between 2-6. Because insulin is the fat storage hormone, as the level increases above 6, more fat storage will take place. As weight begins to increase, mainly around the waistline, insulin resistance ensues causing metabolic dysfunction. This increases the risk of chronic diseases such as diabetes, heart disease, cancer, and dementia.
 
Within the cell are mitochondria (please listen to the short audio on mitochondria) and these ancient bacteria are responsible for glucose conversion into ATP. However, as insulin rises, the waist increases and toxic levels of glucose circulate in the bloodstream, the mitochondria are damaged. Less energy is produced in the cell due to this damage and a typical symptom reported by patients is low energy.
 
There is good news. Reducing the burden on the mitochondria due to excess carbohydrate intake and reducing stress levels (which do cause the breakdown of glucose storage from the liver and muscles) will over time decrease insulin levels (less fat storage). Monitoring insulin levels, A1c, and glucose are standard labs drawn within my practice. If you are gaining weight or have excess weight, it is time to get those levels measured. From there, a treatment plan, which may include medications, is prescribed and I will help get you on your way to an optimal weight and lifestyle plan.